This practical guide from Project Cal-Well shares tips for selecting and implementing universal social, emotional, and behavioral screenings. These screenings support providers to intervene early and ensure that all children have access to supports that they need to be well and achieve personal and academic success. The guide provides characteristics and examples of high-quality screening instruments, guidance on who should conduct screens and when, solutions for addressing concerns about universal screening tools, key resources, and a spotlight on one school district’s efforts to implement universal screenings for student wellness.